WebAfter cessation of methallibure treatment, LH+FSH (50 microng each) administration restored ovarian activity. It is evident from these results that methallibure alters the … WebInhibition of thyroid function and thyrotrophic activity following the administration of methallibure (ICI-33 828). 1975 Feb. 51791. Substance Class: Chemical Created. by admin. on Sat Dec 17 01:54:11 UTC 2024. Edited. by admin. on Sat Dec 17 01:54:11 UTC 2024. Record UNII: MBU5XJ97C4. Record Status: Validated (UNII) Record Version: …
Effects of methallibure on the external morphology, …
WebSUMMARY Gonadotrophin content in the pituitary gland and blood serum as well as ovarian 32P uptake were studied in response to methallibure treatment in H. fossilis. There was a marked reduction in the gonadotrophic activity of the pituitary gland and blood serum within 3 weeks of methallibure treatment (100 μg/g). A simultaneous significant reduction was … Web30 dec. 2000 · The administration of methallibure (2 µg/g BW, daily for 15 days) in Clarias batrachus in prespawning phase (May–June) resulted in decreased weights of seminal … country 840 radio
[PDF] Methallibure, delayed puberty and the pituitary …
WebThe recurrence of delayed puberty in intact rats treated with methallibure is explored and a primary effect on the hypothalamohypophysial complex is presumed to be responsible. Methallibure prevents the onset ofpuberty and ovulation and inhibits pituitary gonadotrophic activity in 30-day-old rats (Walpole, 1968). The compound also reduces food intake … WebGonadotrophin content in the pituitary gland and blood serum as well as ovarian 32P uptake were studied in response to methallibure treatment in H. fossilis. There was a marked reduction in the gonadotrophic activity of the pituitary gland and blood serum within 3 weeks of methallibure treatment (10 … WebAdministration of Methallibure, a non-steroidal gonadotropin (GTH) inhibitor 20 μg g−1 body weight; i.p., daily for 10 days, to prespawning phase female Heteropneustes fossilis inhibited the brain-pituitary-ovarian axis as indicated by significant reductions in plasma and pituitary levels of GTH-II, and plasma levels of 17β-estradiol (E2) and testosterone. country 800